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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Disseminated Mycobacterium tuberculosis in an infant with AIDS
Hossein Masoumi Asl1, Abdolvahab Alborzi, Esmaeel Sadeghi
1Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran. dr_masoumiasl@yahoo.com
Abstract:
Disseminated Mycobacterium tuberculosis with involvement of liver, spleen, and bone marrow is a nonspecific and rare complication in human immunodeficiency virus (HIV) infected infants. Here, we report a six month old girl with fever, recurrent infections, bilateral axilary lymphadenitis, hepatomegaly, huge splenomegaly, and failure to thrive per the Center for Disease Control category of C for AIDS. The infant and her mother had positive enzyme immunoassay (EIA) and Western blot. HIV DNA PCR test of the infant was positive with subtype A (A1) in genotyping. A positive bone marrow aspirate staining for acid fast bacilli and PCR test on culture revealed Mycobacterium tuberculosis.
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