Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recommendations from health research for children and adolescents living in the Kimberley region of Western Australia: a scoping review.

Health policy (Amsterdam, Netherlands)·2026
Same author

What is a clinical trial? A proposal for expanding the WHO definition of a clinical trial for use in mental health research.

The British journal of psychiatry : the journal of mental science·2026
Same author

Associations between prenatal alcohol exposure and parent-reported sleep disturbances in 10,336 adolescents: an Adolescent Brain Cognitive Development study.

Journal of child psychology and psychiatry, and allied disciplines·2026
Same author

Global Seroprevalence of Q Fever Antibodies to Coxiella burnetii in Children and Adolescents: A Systematic Review and Meta-analysis.

The Pediatric infectious disease journal·2026
Same author

Invasive Meningococcal Disease in Australian Children 2016-2022: A Multicenter, Prospective Surveillance Study of Serogroup Distribution and Clinical Presentation in the Meningococcal Vaccine Era.

The Pediatric infectious disease journal·2026
Same author

Australian Guidelines for Assessment and Diagnosis of Fetal Alcohol Spectrum Disorder: Overview of the Development Process and Revised Diagnostic Criteria.

The Medical journal of Australia·2026

Related Experiment Video

Updated: May 31, 2026

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 (BSL-3) Conditions
07:59

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 (BSL-3) Conditions

Published on: September 10, 2021

Gastroenteritis in children.

Jacqueline R Dalby-Payne1, Elizabeth J Elliott

  • 1The Children's Hospital at Westmead, Sydney, Australia.

BMJ Clinical Evidence
|July 6, 2011
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates interventions for preventing and treating acute gastroenteritis in children. Key findings cover rotavirus vaccines, rehydration solutions, and anti-vomiting medications, offering insights into effective management strategies.

More Related Videos

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
06:55

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

Related Experiment Videos

Last Updated: May 31, 2026

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 (BSL-3) Conditions
07:59

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 (BSL-3) Conditions

Published on: September 10, 2021

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
06:55

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Evidence-Based Medicine

Background:

  • Acute gastroenteritis is a common gastrointestinal infection, primarily viral, causing diarrhea, vomiting, and dehydration.
  • Management focuses on fluid replacement to prevent or treat dehydration, regardless of the causative agent.

Purpose of the Study:

  • To systematically review the effects of interventions for preventing acute gastroenteritis in children.
  • To systematically review the effects of treatments for acute gastroenteritis in children.

Main Methods:

  • A systematic review of 20 studies, including systematic reviews, randomized controlled trials (RCTs), and observational studies.
  • Searches conducted across major databases (Medline, Embase, Cochrane Library) up to August 2007.
  • Inclusion of harms alerts from regulatory agencies (FDA, MHRA).

Main Results:

  • Identified 20 relevant studies meeting inclusion criteria.
  • Evaluated the quality of evidence for interventions using the GRADE system.
  • Synthesized information on the effectiveness and safety of various interventions.

Conclusions:

  • Rotavirus vaccines are effective for preventing gastroenteritis.
  • Enteral rehydration solutions and lactose-free feeds are recommended for treatment.
  • Ondansetron shows effectiveness in treating vomiting associated with gastroenteritis.