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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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[Superficial siderosis, an underestimated entity].

S Arion1, P Krolak-Salmon, F Cotton

  • 1Service de radiologie, centre hospitalier Lyon Sud, hospices civils de Lyon, 69495 Pierre Bénite cedex, France. s_arion@hotmail.com

Journal of Neuroradiology = Journal De Neuroradiologie
|July 6, 2011
PubMed
Summary
This summary is machine-generated.

Superficial siderosis of the central nervous system is more common than previously believed, often presenting without classic symptoms. Amyloid angiopathy is a frequent cause in elderly patients, making MRI a key diagnostic tool.

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Area of Science:

  • Neurology
  • Radiology
  • Neuroradiology

Context:

  • Superficial siderosis (SS) involves iron deposition in the central nervous system (CNS).
  • Previous understanding suggested SS is rare, with a characteristic clinical triad.
  • This study examines clinical and MRI findings in a series of SS cases.

Purpose:

  • To review the clinical and MRI characteristics of superficial siderosis of the CNS.
  • To determine the frequency and causes of SS.
  • To evaluate the diagnostic utility of MRI in identifying SS and its etiology.

Summary:

  • Cortical hemosiderin deposits were found in 0.2% of MRIs.
  • The classic triad of hearing loss, ataxia, and pyramidal signs was rare (8%).
  • Amyloid angiopathy was the most common cause (40%), especially in elderly patients.

Impact:

  • Superficial siderosis may be more prevalent than previously thought.
  • Asymptomatic cases are frequent, and the classic triad is uncommon.
  • MRI, particularly in elderly patients, can identify SS and suggest amyloid angiopathy as a likely cause.