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Determination of Vaccine Immunogenicity Using Bovine Monocyte-Derived Dendritic Cells
Published on: May 19, 2023
Serological evidence for BVDV-1 infection in goats in Poland - short communication
Michał Czopowicz1, Jarosław Kaba, Horst Schirrmeier
1Warsaw University of Life Sciences, Department of Large Animal Diseases with the Clinic, Nowoursynowska,Warsaw, Poland. mczopowicz@gmail.com
Abstract:
A serological survey was conducted in 2007 in the breeding goat population in Poland to gain insights into the epidemiology of pestivirus infection. All breeding herds were included in the study and representative serum samples were taken in each herd to evaluate herd-level seroprevalence at 10% expected individual-level prevalence and 95% level of confidence. Altogether 1060 serum samples from 49 herds were tested with blocking ELISA and then the positive and inconclusive results were confirmed in a serum neutralisation test, which also allowed us to determine the pestivirus species responsible for seroconversion. Herd-level seroprevalence proved to be 10.2% and bovine viral diarrhoea virus type 1 (BVDV-1) was responsible for the seroconversion in seven out of eight cases. In the remaining serum sample the causative virus could not be identified due to a pronounced cross-neutralising activity possibly derived from multiple infections. This is the first report on the diagnosis of BVDV-1 infection in Polish goats.
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