Related Experiment Video
Updated: May 31, 2026

08:23
Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages
Published on: May 30, 2019
Neonatal Plasmodium vivax malaria: an overlooked entity
Akanksha Gandhi1, Kirti Garg, Neelam Wadhwa
1Department of Pathology, University College of Medical Sciences, University of Delhi, Shahdra, Delhi, India. drakanshagandhi@yahoo.co.in
Journal of Infection in Developing Countries
|July 6, 2011
Summary
Neonatal malaria, though rare in India, requires routine screening in febrile infants. Early diagnosis and treatment are crucial for preventing infant mortality in malaria-endemic regions.
Area of Science:
- Tropical Medicine
- Pediatrics
- Infectious Diseases
Background:
- Malaria is a significant public health concern in India, predominantly affecting adults and older children.
- Neonatal malaria is historically considered an uncommon clinical presentation in endemic areas.
Observation:
- A case of a 26-day-old neonate presenting with persistent fever and splenomegaly is detailed.
- The neonate underwent extensive diagnostic workup for splenomegaly before malaria was considered.
Findings:
- The neonate was ultimately diagnosed with malaria after a prolonged and challenging diagnostic process.
- This case highlights the potential for malaria to manifest in neonates, even in regions where it's considered rare.
Implications:
- Routine malaria screening should be integrated into the diagnostic protocols for all neonates presenting with fever in malaria-endemic zones.
- Prompt diagnosis and initiation of malaria treatment in neonates can significantly reduce the risk of severe illness and mortality.
- Raising awareness among healthcare providers about neonatal malaria is essential for timely and effective management.
Related Concept Videos
Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Diversity of Protists II
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
Fungal Phylum Microsporidia
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...

