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Related Experiment Video

Updated: May 31, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Bullous pemphigoid.

Sujay Khandpur¹, Parul Verma

¹Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India. sujay_khandpur@yahoo.com

Indian Journal of Dermatology, Venereology and Leprology

|July 6, 2011

Summary

This summary is machine-generated.

Bullous pemphigoid (BP) is a common autoimmune skin disease in India, primarily affecting the elderly with itchy blisters. Diagnosis involves histology and immunofluorescence, with treatment varying by disease severity.

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Granulocyte-dependent Autoantibody-induced Skin Blistering

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Published on: October 12, 2012

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

Area of Science:

Dermatology
Immunology
Autoimmune Diseases

Background:

Bullous pemphigoid (BP) is a prevalent autoimmune blistering disease in India.
It typically affects the elderly, presenting as tense blisters on an inflamed base, often on flexural areas and accompanied by intense itching.

Purpose of the Study:

To provide an overview of bullous pemphigoid in the Indian context.
To discuss diagnostic methods and treatment strategies for BP.

Main Methods:

Review of existing literature on bullous pemphigoid.
Discussion of diagnostic confirmation through histology and immunofluorescence.
Exploration of various therapeutic approaches.

Main Results:

BP diagnosis can be confirmed using established methods like histology and immunofluorescence.
Newer diagnostic techniques are emerging.
Treatment efficacy varies depending on the chosen anti-inflammatory and immunosuppressive agents.

Conclusions:

Bullous pemphigoid is a significant dermatological condition in India requiring accurate diagnosis and tailored treatment.
Management strategies should consider disease extent and progression for optimal outcomes.