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Updated: May 31, 2026
09:06
Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
Published on: March 25, 2020
Vitamins and cutaneous wound healing.
S Sinno1, D S Lee, A Khachemoune
1Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.
Journal of Wound Care
|July 6, 2011
Summary
Vitamins A, C, E, D, K, and B show promise in wound healing. Further research is needed to fully understand their role in wound care and optimize their use.
Area of Science:
- Nutritional Science
- Dermatology
- Regenerative Medicine
Background:
- Vitamins are hypothesized to influence wound healing through various mechanisms.
- The role of vitamins in modulating wound repair requires thorough investigation.
Purpose of the Study:
- To review scientific literature on the role of different vitamins in wound healing.
- To explore the proposed mechanisms by which vitamins impact wound repair.
Main Methods:
- Searched MEDLINE, Cochrane Database of Systematic Reviews, and Google Scholar.
- Included basic science and clinical studies on vitamins as adjuncts in wound healing.
Main Results:
- Major vitamins (A, C, E, D, K, B) demonstrated utility in wound care.
- Mechanisms of action for key vitamins in wound healing were reviewed.
- Evidence from basic science and clinical trials supports vitamin efficacy.
Conclusions:
- Extensive literature exists on vitamins' effects on wound healing at the basic science level.
- Further controlled trials are necessary to elucidate optimal vitamin utilization in clinical wound care.
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Formation of Blood Clot
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The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
01:30Vitamins
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01:19Overview of Regeneration and Repair
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
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Regeneration
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