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Prenatal diagnosis of fetal left ventricular non-compaction cardiomyopathy

E G Tsapakis1, M Eleftheriades, G Daskalakis

  • 1Embryocare, Fetal Medicine Unit, Athens, Greece.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
|July 6, 2011
PubMed

Insights

Isolated left ventricular non-compaction (LVNC) is a rare genetic cardiomyopathy. This case report details a prenatal diagnosis of LVNC at 25 weeks gestation.

Area of Science:

  • Cardiology
  • Genetics
  • Prenatal Diagnosis

Background:

  • Isolated left ventricular non-compaction (LVNC) is a rare cardiomyopathy.
  • It is characterized by prominent trabeculae and deep recesses in the left ventricle.
  • LVNC is classified as a primary genetic cardiomyopathy or unclassified cardiomyopathy.

Observation:

  • This report presents a case of LVNC detected prenatally.
  • The diagnosis was made at 25 + 4 weeks of gestation.

Findings:

  • The case demonstrates the feasibility of prenatal detection of LVNC.
  • Key features include thickened myocardium with compacted and non-compacted layers.

Implications:

  • Prenatal diagnosis of LVNC allows for early management and genetic counseling.
  • This case highlights the importance of advanced imaging in identifying congenital heart anomalies.
  • Further research into the genetic basis and long-term outcomes of prenatally diagnosed LVNC is warranted.

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