Related Experiment Video
Updated: May 31, 2026

Rodent Model of Masseter Volumetric Muscle Loss for Studying Bioengineering Materials
Published on: May 31, 2024
Ewing's sarcoma of the masseter muscle
H A Osborn1, B Wehrli, J H Franklin
1Schulich School of Medicine, University of Western Ontario, London, Canada.
Objective:
To present a case of extraskeletal Ewing's sarcoma originating in the masseter muscle, and to review the diagnosis and management of these rare tumours.
Methods:
Case report and literature review.
Results:
We report a patient with Ewing's sarcoma of the masseter muscle with mandibular invasion. She was treated with induction chemotherapy, salvage surgery and free flap reconstruction.
Conclusion:
This case highlights the management of these rare tumours. Aggressive multi-modal treatment, including multi-agent chemotherapy, surgical resection and irradiation, appears to offer the best prognosis. Contemporary reconstructive techniques can restore function and form in cases with challenging defects.

