Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
Body Temperature01:07

Body Temperature

Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C (97–99°F), remaining relatively stable...
Body Temperature01:25

Body Temperature

The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sleep-Disordered Breathing in Newborns After Myelomeningocele Repair.

Pediatrics·2026
Same author

The Use of Extracorporeal Membrane Oxygenation in Neonates With Congenital Renal Failure.

Journal of pediatric surgery·2025
Same author

Testosterone Effects on Short-term Physical, Hormonal, and Neurodevelopmental Outcomes (TESTO) in Infants With 47,XXY.

The Journal of clinical endocrinology and metabolism·2025
Same author

Testosterone Effects on Short-Term Physical, Hormonal, and Neurodevelopmental Outcomes in Infants with 47,XXY/Klinefelter Syndrome: The TESTO Randomized Controlled Trial.

medRxiv : the preprint server for health sciences·2024
Same author

The Effect of Steroids on Prenatally Diagnosed Lung Lesions.

Journal of pediatric surgery·2023
Same author

Prenatally-diagnosed renal failure: an ethical framework for decision-making.

Journal of perinatology : official journal of the California Perinatal Association·2023

Related Experiment Video

Updated: May 31, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

"Caution! Contents should be cold": developing a whole-body hypothermia program.

Regina Reynolds1, Samara Talmage

  • 1NICU. gina.reynolds@baylorhealth.edu

Neonatal Network : NN
|July 7, 2011
PubMed
Summary
This summary is machine-generated.

Hypoxic-ischemic encephalopathy (HIE) is a brain injury in newborns. Therapeutic hypothermia, initiated within six hours of birth, can reduce brain injury in infants with HIE.

More Related Videos

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Related Experiment Videos

Last Updated: May 31, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
05:00

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

Published on: March 3, 2021

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Area of Science:

  • Neonatal Medicine
  • Neurology
  • Pediatric Critical Care

Background:

  • Hypoxic-ischemic encephalopathy (HIE) causes brain injury due to oxygen deprivation in newborns.
  • Therapeutic hypothermia (whole-body or head cooling) is increasingly used for moderate-to-severe HIE.
  • These cooling methods mitigate reperfusion injury to the brain.

Purpose of the Study:

  • To provide care recommendations for bedside clinicians managing infants with HIE.
  • To outline a clinical care path for infants undergoing therapeutic hypothermia.
  • To emphasize the timely initiation of hypothermia treatment.

Main Methods:

  • Review of current therapeutic hypothermia practices for neonatal HIE.
  • Development of clinical care recommendations for healthcare professionals.
  • Focus on the critical six-hour window for initiating treatment.

Main Results:

  • Therapeutic hypothermia demonstrates efficacy in reducing reperfusion injury in HIE.
  • Early initiation (within six hours of birth) is crucial for optimal outcomes.
  • Structured clinical pathways are essential for managing these infants.

Conclusions:

  • Neonatal therapeutic hypothermia is a vital intervention for HIE.
  • Prompt and organized care is necessary for successful treatment.
  • Clinicians require clear guidelines for implementing hypothermia protocols.