Related Experiment Videos
Epidermal growth factor increases cyclic AMP levels in pregnant rat mammary gland explants
S Lavandero1, M P Ocaranza, M Sapag-Hagar
1Departamento de Bioquimica y Biologia Molecular, Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile, Santiago.
Research Communications in Chemical Pathology and Pharmacology
|September 1, 1990
Abstract:
Addition of epidermal growth factor (EGF) to a rat mammary organ culture results in increase levels of intracellular cyclic AMP. This dose dependent EGF effect occurs at physiological concentrations of the hormone and was maximal in early and middle pregnancy.