Related Experiment Videos
Relative binding constants of arsenical-antidote adducts determined by NMR spectroscopy
R J O'Connor1, E L McGown, K Dill
1Biophysical Research Division, Letterman Army Institute of Research, Presidio of San Francisco, CA 94129-6800.
Research Communications in Chemical Pathology and Pharmacology
|September 1, 1990
Abstract:
Proton nuclear magnetic resonance spectroscopy was used to determine relative binding constants for several arsenical-antidote adducts. It was found that BAL (2,3-dimercaptopropanol) and DMPS (2,3-dimercaptopropanesulfonic acid) had a higher affinity than DMSA (2,3-dimercaptosuccinic acid) for the two organic arsenicals studied.