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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.

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Updated: May 31, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Diabetes and periodontitis.

Kalyani Deshpande1, Ashish Jain, Ravikant Sharma

  • 1Department of Biochemistry, Dr. HS Judge Institute of Dental Sciences & Hospital, Panjab University, Sector 25, Chandigarh, India.

Journal of Indian Society of Periodontology
|July 7, 2011
PubMed
Summary
This summary is machine-generated.

Diabetes significantly worsens periodontal disease, especially with long-term hyperglycemia. Further research is needed to understand the impact of periodontal disease on diabetes and patient awareness of oral hygiene is crucial.

Keywords:
Diabeteshyperglycemiaperiodontal diseaserisk factors

Related Experiment Videos

Last Updated: May 31, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Area of Science:

  • Periodontology
  • Endocrinology
  • Public Health

Background:

  • Diabetes mellitus and periodontal diseases are chronic conditions with a complex bidirectional relationship.
  • Existing literature often details definitions, prevalence, and complications, but a comprehensive update on their interplay is needed.

Purpose of the Study:

  • To review current knowledge on the relationship between diabetes mellitus and periodontal diseases.
  • To clarify the influence of periodontal disease on diabetes metabolic control and vice versa.
  • To explore underlying mechanisms and the effect of periodontal interventions.

Main Methods:

  • Systematic review of human epidemiological studies, including cross-sectional, longitudinal cohort, and case-control designs.
  • Analysis focused on research published within the last 30 years.
  • Synthesis of predominant findings from selected articles.

Main Results:

  • Diabetes mellitus is confirmed as a significant risk factor for periodontitis.
  • Periodontitis is notably more severe in diabetic patients with chronic hyperglycemia.
  • Emerging evidence suggests various underlying mechanisms, though further investigation is required.

Conclusions:

  • Diabetes exacerbates periodontal disease, highlighting the need for improved glycemic control.
  • Further research is essential to fully elucidate the impact of periodontal diseases on diabetes.
  • Patient education on regular periodontal maintenance and oral hygiene is critical.