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Related Experiment Video

Updated: May 31, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Clear cell unicystic ameloblastoma.

Mb Radhika1, Lalita J Thambiah, K Paremala

  • 1Department of Oral Pathology, Krishnadevaraya College of Dental Sciences, MVIT Campus, Near Yelahanka, Hunusamaranahalli, Bangalore, India.

Journal of Oral and Maxillofacial Pathology : JOMFP
|July 7, 2011
PubMed
Summary

This study reports a rare case of unicystic ameloblastoma with clear cell differentiation and multiple histologic variants in a young female. Surgical treatment showed no recurrence after 20 months, highlighting effective management of this rare odontogenic tumor.

Keywords:
Ameloblastomaclear cellunicystic variant

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Last Updated: May 31, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

  • Oral pathology
  • Odontogenic tumors
  • Histopathology

Background:

  • Unicystic ameloblastoma is a rare variant of ameloblastoma, often presenting clinically as a jaw swelling.
  • Clear cell differentiation within unicystic ameloblastoma, alongside other histologic patterns, is exceptionally uncommon.
  • Accurate histopathological diagnosis is crucial for appropriate management and prognosis.

Observation:

  • A case of a large, well-circumscribed mandibular swelling in a 22-year-old female is presented.
  • Histopathological examination revealed unicystic ameloblastoma with clear cell differentiation and diverse histologic patterns.
  • The tumor exhibited features of both unicystic ameloblastoma and other ameloblastoma variants.

Findings:

  • The diagnosed unicystic ameloblastoma demonstrated a rare combination of clear cell differentiation and multiple histologic variants.
  • Surgical enucleation and chemical cauterization were performed as treatment modalities.
  • A 20-month follow-up indicated no evidence of tumor recurrence post-surgery.

Implications:

  • This case underscores the importance of thorough histopathological evaluation for diagnosing rare variants of ameloblastoma.
  • The successful surgical management suggests that enucleation and cauterization can be effective for this specific type of tumor.
  • Further research into the behavior and optimal treatment of clear cell differentiating unicystic ameloblastoma is warranted.