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Related Experiment Video

Updated: May 31, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

Looking beyond the D-dimer.

Michael S Kelleher¹, Howard A Selinger

¹University of Connecticut School of Medicine, Farmington, CT, USA. mkelleher@student.uchc.edu

The Journal of Family Practice

|July 7, 2011

Summary

This summary is machine-generated.

The D-dimer test can help rule out pulmonary embolism. However, persistent signs and symptoms warrant further investigation despite a negative D-dimer result.

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Area of Science:

Medical Diagnostics
Cardiology
Pulmonary Medicine

Background:

Pulmonary embolism (PE) is a serious condition affecting blood flow to the lungs.
The D-dimer blood test is a common diagnostic tool used to help exclude PE.

Observation:

A patient presented with clinical signs and symptoms suggestive of pulmonary embolism.
Initial D-dimer testing yielded a negative result, seemingly ruling out PE.

Findings:

Despite the negative D-dimer, the patient's clinical presentation indicated a potential for pulmonary embolism.
This highlights the limitations of D-dimer testing in certain clinical scenarios.

Implications:

Clinicians should consider the full clinical picture, not solely rely on D-dimer results.
Further diagnostic evaluation may be necessary even with a negative D-dimer if suspicion for PE remains high.