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Updated: May 31, 2026

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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Piperazic acid-containing natural products: isolation, biological relevance and total synthesis
Alexander J Oelke1, David J France, Tatjana Hofmann
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
Natural Product Reports
|July 7, 2011
Abstract:
Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biological activities, and presents an overview of recent total syntheses of these molecules.

