Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Renal Corpuscle01:20

Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safe causal-graph primal-dual multi-agent scheduling for energy- and latency-constrained edge-assisted cognitive radio networks.

Scientific reports·2026
Same author

In response to the Letter to the Editor on our Case Report "Serotonin syndrome following spinal anaesthesia for elective caesarean delivery".

International journal of obstetric anesthesia·2026
Same author

Serotonin syndrome following spinal anaesthesia for elective caesarean delivery: a case report.

International journal of obstetric anesthesia·2025
Same author

A semi-supervised deep neuro-fuzzy iterative learning system for automatic segmentation of hippocampus brain MRI.

Mathematical biosciences and engineering : MBE·2025
Same author

Gender differences in COVID-19 knowledge, risk perception, and public stigma among the general community: Findings from a nationwide cross-sectional study in India.

International journal of disaster risk reduction : IJDRR·2023
Same author

Pharmacokinetics of rifampicin, isoniazid & pyrazinamide during daily & intermittent dosing: A preliminary study.

The Indian journal of medical research·2023

Related Experiment Video

Updated: May 31, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
06:38

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Extrarenal teratoid Wilms' tumour.

A K Chowhan1, M K Reddy, V Javvadi

  • 1Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati 517507, Andhra Pradesh, India. chowhanpath@gmail.com

Singapore Medical Journal
|July 7, 2011
PubMed
Summary

This case study details a rare extrarenal teratoid Wilms' tumour in a child. The retroperitoneal tumor exhibited triphasic elements and heterologous teratoid components, offering insights into its development.

Related Experiment Videos

Last Updated: May 31, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
06:38

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Area of Science:

  • Pediatric Oncology
  • Pathology
  • Developmental Biology

Background:

  • Wilms' tumour typically originates in the kidney.
  • Extrarenal Wilms' tumours are exceptionally rare, posing diagnostic challenges.
  • Teratoid Wilms' tumours represent a specific subtype with complex histology.

Observation:

  • A 15-month-old male presented with a retroperitoneal mass.
  • Histopathological analysis revealed a triphasic Wilms' tumour with heterologous teratoid elements.
  • The teratoid components included glandular epithelium, skeletal muscle, adipose, and neuroglial tissues.

Findings:

  • The tumour demonstrated features of both Wilms' tumour and teratoma.
  • Detailed histochemical and immunohistochemical analyses were performed.
  • The presence of diverse heterologous tissues suggests a complex histogenesis.

Implications:

  • This case expands the understanding of rare pediatric neoplasms.
  • It highlights the importance of comprehensive histopathological evaluation for accurate diagnosis.
  • Further research into the embryogenesis of extrarenal teratoid Wilms' tumours is warranted.