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Related Experiment Video

Updated: May 31, 2026

Optic Nerve Transection: A Model of Adult Neuron Apoptosis in the Central Nervous System
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Published on: May 12, 2011

Ocular surface changes after lateral rectus muscle recession.

Sohee Jeon1, Shin Hae Park, Jun-Sub Choi

  • 1Department of Ophthalmology and Visual Science, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
|July 8, 2011
PubMed
Summary
This summary is machine-generated.

Strabismus surgery temporarily impacts the ocular surface, causing dry eye symptoms and tear film instability due to reduced goblet cell density. Most ocular surface parameters return to normal within four months post-surgery.

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Area of Science:

  • Ophthalmology
  • Ocular Surface Disease
  • Strabismus Surgery

Background:

  • Strabismus surgery can affect the ocular surface and lacrimal gland function.
  • Understanding these changes is crucial for managing post-operative discomfort.

Purpose of the Study:

  • To evaluate the impact of strabismus surgery on the integrated ocular surface/lacrimal gland unit.
  • To assess changes in dry eye symptoms, tear film stability, and conjunctival parameters.

Main Methods:

  • Prospective study of 23 patients undergoing lateral rectus muscle recession.
  • Evaluated dry eye questionnaire, corneal staining, sensitivity, tear film break-up time, Schirmer I test, and impression cytology (goblet cell density - GCD).
  • Measurements taken preoperatively and at 1, 2, 3, and 4 months postoperatively.

Main Results:

  • Increased dry eye symptoms and corneal staining post-surgery, returning to baseline by 4 months and 2 months, respectively.
  • Decreased tear film break-up time persisted up to 4 months.
  • Significantly reduced goblet cell density (GCD) observed up to 2 months postoperatively.

Conclusions:

  • Tear film instability and ocular irritation symptoms after strabismus surgery may stem from GCD depletion and altered conjunctival sensitivity.
  • Ocular surface parameters generally recover to baseline levels by 4 months post-surgery.