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Selective laser trabeculoplasty in uncontrolled pseudoexfoliation glaucoma
Modi Goldenfeld1, Orna Geyer, Eitan Segev
1The Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel. audreykap@gmail.com
Summary
Selective laser trabeculoplasty (SLT) effectively lowers intra-ocular pressure (IOP) in pseudoexfoliation glaucoma (PEXG) patients. This safe treatment reduces the need for glaucoma medications within one year.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Laser Therapy
Background:
- Pseudoexfoliation glaucoma (PEXG) presents unique challenges in intra-ocular pressure (IOP) management.
- Uncontrolled PEXG often requires effective and safe treatment modalities.
Purpose of the Study:
- To evaluate the efficacy of selective laser trabeculoplasty (SLT) for uncontrolled pseudoexfoliation glaucoma (PEXG).
- To assess the safety profile of SLT in this patient population.
Main Methods:
- Fifty-seven patients with uncontrolled PEXG underwent SLT.
- Intra-ocular pressure (IOP) was monitored preoperatively and at multiple intervals up to 12 months post-SLT.
- Topical anti-glaucoma medications were adjusted as needed during follow-up.
Main Results:
- Mean IOP significantly decreased by 31.5% from 26.01 to 17.8 mm Hg one year post-SLT (P < .001).
- The average number of medications per patient reduced from 2.8 to 2.3.
- Transient IOP spikes occurred in 3.5% of eyes, resolving within 24 hours; conjunctival redness and infection were noted in 67% of eyes within 1 day.
Conclusions:
- Selective laser trabeculoplasty (SLT) demonstrates significant efficacy in reducing IOP for patients with pseudoexfoliation glaucoma (PEXG).
- SLT is a safe and effective treatment option for managing uncontrolled PEXG.
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