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Vessel-sparing Excision and Primary Anastomosis
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Published on: January 7, 2019

Delayed proximal ureteric stricture formation after complex partial nephrectomy.

Jose M Reyes1, Daniel J Canter, Mohit Sirohi

  • 1Division of Urologic Oncology, Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.

BJU International
|July 8, 2011
PubMed
Summary
This summary is machine-generated.

Delayed ureteric stricture (US) after complex nephron-sparing surgery (NSS) is uncommon. Risk factors include tumor complexity and postoperative complications like urinary leaks or hemorrhage.

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Area of Science:

  • Urology
  • Oncology
  • Surgical Innovation

Background:

  • Nephron-sparing surgery (NSS) is a standard treatment for kidney cancer.
  • Delayed ureteric stricture (US) is a potential complication following NSS.
  • Understanding the incidence and risk factors for US after complex NSS is crucial for patient outcomes.

Purpose of the Study:

  • To determine the incidence of delayed ureteric stricture (US) after complex nephron-sparing surgery (NSS).
  • To review patient and tumor characteristics associated with delayed US.
  • To identify potential risk factors for US formation post-NSS.

Main Methods:

  • Retrospective review of a kidney cancer institutional database.
  • Analysis of 720 patients who underwent NSS between 2000 and 2010.
  • Identification and characterization of 11 patients who developed delayed US.

Main Results:

  • The incidence of delayed US after complex NSS was 1.5% (11 out of 720 patients).
  • Commonly associated factors included postoperative urinary leak (72.7%) and retroperitoneal hemorrhage (18.2%).
  • Strictures occurred in the upper ureter, diagnosed at a median of 154 days postoperatively.

Conclusions:

  • Delayed ureteric stricture (US) is an uncommon but under-reported complication of complex NSS.
  • Tumor complexity, imperative indications, tumor location, and postoperative complications are potential risk factors.
  • Patients undergoing NSS for complex renal masses require counseling and vigilant postoperative surveillance for US.