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Updated: May 31, 2026

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

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Published on: June 30, 2014

Multiple sclerosis relapses are not associated with exercise.

A Tallner¹, A Waschbisch, I Wenny

¹Institute of Sport Science and Sport, University of Erlangen-Nürnberg, Germany.

Multiple Sclerosis (Houndmills, Basingstoke, England)

|July 8, 2011

Summary

This summary is machine-generated.

Physical activity does not worsen multiple sclerosis (MS) relapses. Exercise in MS patients showed no link to increased disease activity, with highly active individuals experiencing fewer relapses.

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Area of Science:

Neurology
Exercise Science
Immunology

Background:

Multiple sclerosis (MS) commonly affects young, active individuals.
The impact of physical activity on MS disease activity remains a critical question.

Purpose of the Study:

To investigate the relationship between sports activity levels and relapse rates in patients with multiple sclerosis.
To determine if exercise influences the clinical course of MS.

Main Methods:

A self-report questionnaire assessed sports activity in 632 MS patients.
Objective clinical data and physical fitness parameters were evaluated in a subgroup to validate self-reported data.

Main Results:

No significant association was found between sports activity and clinical relapses in MS patients.
The most active group exhibited the lowest mean, standard deviation, and range of relapses.

Conclusions:

Physical activity does not appear to significantly influence clinical disease activity in multiple sclerosis.
Exercise may potentially be associated with a reduced relapse rate, warranting further investigation.