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Related Experiment Video

Updated: May 31, 2026

Models of Bone Metastasis
08:49

Models of Bone Metastasis

Published on: September 4, 2012

Radiation for bone metastases.

Daniel J Bourgeois1, Stephen Kraus, Bassam N Maaloof

  • 1Tulane Medical School, New Orleans, Los Angeles and USA.

Current Opinion in Supportive and Palliative Care
|July 8, 2011
PubMed
Summary
This summary is machine-generated.

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Radiation therapy effectively palliates painful bone metastases in prostate cancer patients. Single-fraction radiation is underutilized despite evidence supporting its efficacy for pain relief.

Area of Science:

  • Oncology
  • Radiotherapy
  • Palliative Care

Background:

  • Bone metastases are a common complication of advanced prostate cancer, causing significant pain and reduced quality of life.
  • External beam radiation therapy (EBRT) is a cornerstone treatment for palliation of painful bone metastases.

Purpose of the Study:

  • To review the current state-of-the-art in radiation and treatment of painful bone metastases, with a specific focus on prostate cancer.
  • To highlight evolving strategies and their clinical application.

Main Methods:

  • Systematic review of recent randomized studies and national/international guidelines.
  • Analysis of the efficacy of different radiation modalities, including external beam radiation and systemic radioisotopes.

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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

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Last Updated: May 31, 2026

Models of Bone Metastasis
08:49

Models of Bone Metastasis

Published on: September 4, 2012

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Main Results:

  • Single-fraction EBRT regimens demonstrate efficacy in palliating pain from bone metastases.
  • Despite supporting data and guidelines, single-fraction regimens are underutilized in the USA.
  • Beta-emitting isotopes are effective systemic agents; novel alpha-emitters like radium-223 show promise for survival benefit in advanced prostate cancer.

Conclusions:

  • Various forms of radiation therapy are highly effective for palliating pain associated with bone metastases.
  • Further research and implementation of evidence-based guidelines are needed to optimize patient care.