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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...

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Updated: May 31, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Inflammatory bowel disease in pregnancy.

Dawn B Beaulieu1, Sunanda Kane

  • 1Division of Gastroenterology, Vanderbilt University, Nashville, TN 37232, USA.

World Journal of Gastroenterology
|July 8, 2011
PubMed
Summary

For women with inflammatory bowel disease (IBD), maintaining disease remission before and during pregnancy is key for healthy outcomes. Active IBD increases risks for preterm labor and low birth weight in infants.

Keywords:
BreastfeedingCrohn’s diseaseInflammatory bowel diseasePregnancyUlcerative colitis

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Chronic Salmonella Infection Induced Intestinal Fibrosis
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Area of Science:

  • Gastroenterology
  • Obstetrics
  • Reproductive Health

Background:

  • Crohn's disease and ulcerative colitis impact women of childbearing age.
  • Family planning is a frequent topic for patients with inflammatory bowel disease (IBD).

Purpose of the Study:

  • To review the importance of disease control in IBD patients planning pregnancy.
  • To highlight the impact of active versus quiescent disease on pregnancy outcomes.

Main Methods:

  • Literature review on IBD management during pregnancy.
  • Analysis of studies correlating disease activity with pregnancy complications.

Main Results:

  • Quiescent IBD before conception correlates with pregnancy outcomes similar to the general population.
  • Active IBD during pregnancy is associated with increased risks of preterm labor, low birth weight, and small for gestational age infants.

Conclusions:

  • Continued medical management throughout pregnancy is crucial for optimizing outcomes in IBD patients.
  • A collaborative approach between gastroenterologists and obstetricians, alongside patient education, is vital for successful maternal and infant outcomes.