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Updated: May 31, 2026
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A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
Published on: May 21, 2010
Hashimoto encephalopathy presenting with progressive cerebellar ataxia.
H Nakagawa1, M Yoneda, A Fujii
1Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
BMJ Case Reports
|July 8, 2011
Summary
Hashimoto encephalopathy can manifest as isolated cerebellar ataxia. Prompt steroid treatment led to significant improvement, highlighting the condition's responsiveness to immunosuppression.
Area of Science:
- Neurology
- Immunology
- Endocrinology
Background:
- Hashimoto encephalopathy presents with diverse neuropsychiatric symptoms.
- Anti-thyroid antibodies aid diagnosis but are not definitive due to high prevalence in the general population.
Purpose of the Study:
- To describe a case of Hashimoto encephalopathy presenting with isolated cerebellar ataxia.
- To emphasize the condition's response to immunosuppressive therapy.
Main Methods:
- Clinical case presentation.
- Electroencephalography (EEG) for neurological assessment.
- Therapeutic trial with steroid administration.
Main Results:
- The patient exhibited progressive cerebellar ataxia.
- EEG showed mild abnormalities.
- Significant clinical improvement was observed following steroid treatment.
Conclusions:
- Hashimoto encephalopathy can present with isolated cerebellar ataxia.
- Immunosuppressive therapy, such as steroids, is effective in managing Hashimoto encephalopathy.
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