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iChip

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...

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Related Experiment Video

Updated: May 31, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

'Fab-chips': a versatile, fabric-based platform for low-cost, rapid and multiplexed diagnostics.

Paridhi Bhandari¹, Tanya Narahari, Dhananjaya Dendukuri

¹Achira Labs Pvt. Ltd., 108/27, 29th Main, 23rd Cross, BTM-II, Bangalore, 560076, India.

|July 8, 2011

Summary

Weaving silk yarns creates low-cost, scalable fabric chips for point-of-care testing. This method enables precise control over fluid flow and reagent integration for simple diagnostic assays.

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Last Updated: May 31, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

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Published on: September 19, 2017

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Published on: October 20, 2018

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

Area of Science:

Materials Science
Biomedical Engineering
Textile Engineering

Background:

Developing low-cost, scalable manufacturing for lab-on-chip devices is crucial for point-of-care testing.
Existing methods often face challenges in cost-effectiveness and large-scale production.

Purpose of the Study:

To introduce weaving as a unified, scalable, and low-cost platform for manufacturing fabric chips.
To demonstrate the fabrication of integrated fabric chips for diagnostic applications.

Main Methods:

Silk yarns with varying properties were selected, treated with reagents, dried, and handloom-woven.
Pre-defined flow paths were created using wetting/non-wetting yarns and a Jacquard loom attachment.
Yarn parameters (twist frequency, coverage area) were manipulated to tune wicking rate and absorptive capacity.

Main Results:

A scalable and low-cost manufacturing platform for fabric chips was established.
Control over fluid dynamics within the fabric was achieved through yarn selection and weaving techniques.
Proof-of-concept immunoassay was successfully performed on reagent-coated fabric chip strips using capillary action.

Conclusions:

Weaving offers a versatile and cost-effective approach for fabricating functional fabric-based diagnostic devices.
The developed platform facilitates the integration of reagents and control of fluid flow for point-of-care applications.
This technology holds significant potential for advancing accessible and rapid diagnostic testing.