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Updated: May 31, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Common variants for atrial fibrillation: results from genome-wide association studies
Xinyuan Liu1, Fei Wang, Ashley C Knight
1Department of Pediatrics, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China.
Abstract:
Atrial fibrillation (AF) affects more than 5 million people worldwide; however, none of the anti-arrhythmic drugs available now are entirely optimal in terms of efficacy and safety. A better understanding of the molecular mechanism of AF will facilitate the process of finding new strategies to prevent AF. As the non-familial AF is the major form of AF, identifying common variants for AF in these populations by genome-wide association studies will definitely accelerate this process. This review summarizes the recently identified common AF variants on 4q25, 16q22, and 1q21 and discusses their implications for the clinic.
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