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Updated: May 31, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
MR imaging findings in 76 consecutive surgically proven cases of pericardial disease with CT and pathologic
Phillip M Young1, James F Glockner, Eric E Williamson
1Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN, USA. young.phillip@mayo.edu
Abstract:
To describe findings of patients with surgically confirmed pericardial disease on state of the art MR sequences. Retrospective review was performed for patients who underwent pericardiectomy and preoperative MR over a 5 year period ending in 2009. Patients' records were reviewed to confirm the diagnosis of chronic recurrent pericarditis, constrictive pericarditis, or pericardial tumor. MR imaging findings of pericardial thickness, IVC diameter, presence or absence of pericardial or pleural effusion, pericardial edema, pericardial enhancement, and septal "bounce" were recorded. Patients with constriction had a larger IVC diameter (3.1 ± 0.4 cm) than patients with recurrent pain and no constriction (2.0 ± 0.4 cm). Mean pericardial thickness for the 16 patients with chronic recurrent pericarditis but no evidence of constriction was 4.8 ± 2.9 mm. Mean pericardial thickness for patients with constriction was 9.2 ± 7.0 cm with calcification, and 4.6 ± 2.1 cm without calcification. 94% of patients with chronic recurrent pericarditis had gadolinium enhancement of the pericardium, while 76% of patients with constriction had pericardial enhancement. Septal "bounce" was present in 19% of chronic recurrent pericarditis cases and 86% of constriction cases. 5 patients had a pericardial neoplasm, 1 of which was not identified preoperatively. State of the art MR techniques can identify significant and distinct findings in patients with chronic recurrent pericarditis, constrictive pericarditis, and pericardial tumors.
Insights
State-of-the-art Magnetic Resonance (MR) imaging effectively differentiates chronic recurrent pericarditis, constrictive pericarditis, and pericardial tumors. Key findings include distinct pericardial thickness, IVC diameter, and septal bounce patterns.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Pericardial diseases, including chronic recurrent pericarditis, constrictive pericarditis, and pericardial tumors, require accurate diagnostic methods.
- Distinguishing between these conditions is crucial for appropriate patient management and treatment.
Purpose of the Study:
- To evaluate the utility of advanced Magnetic Resonance (MR) imaging sequences in characterizing patients with surgically confirmed pericardial disease.
- To identify distinct MR imaging findings associated with different types of pericardial pathology.
Main Methods:
- Retrospective review of patients who underwent pericardiectomy and preoperative MR imaging over a 5-year period.
- Analysis of MR findings including pericardial thickness, inferior vena cava (IVC) diameter, effusions, edema, enhancement, and septal bounce.
- Correlation of imaging findings with confirmed diagnoses of chronic recurrent pericarditis, constrictive pericarditis, or pericardial tumor.
Main Results:
- Patients with constrictive pericarditis exhibited a larger IVC diameter (3.1 ± 0.4 cm) compared to those with recurrent pericarditis without constriction (2.0 ± 0.4 cm).
- Pericardial thickness varied, with higher mean thickness noted in constrictive cases with calcification (9.2 ± 7.0 cm).
- Septal bounce was significantly more prevalent in constrictive pericarditis (86%) than in chronic recurrent pericarditis (19%). Gadolinium enhancement was common in both (94% vs. 76%).
Conclusions:
- Advanced MR imaging techniques provide significant and distinct findings for differentiating chronic recurrent pericarditis, constrictive pericarditis, and pericardial tumors.
- Specific MR parameters like IVC diameter and septal bounce are valuable in diagnosing constrictive pericarditis.
- MR imaging is a powerful tool for evaluating pericardial disease, aiding in preoperative diagnosis and surgical planning.
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