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Related Concept Videos

Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
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Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide generation. 
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
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Inflammatory Bowel Disease IV: Pharmacological Management

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Related Experiment Video

Updated: May 31, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
06:06

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Interventions for treating oral lichen planus.

Kobkan Thongprasom1, Marco Carrozzo, Susan Furness

  • 1Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand, 10330.

The Cochrane Database of Systematic Reviews
|July 8, 2011
PubMed
Summary
This summary is machine-generated.

This review found insufficient evidence to support the effectiveness of specific treatments for oral lichen planus (OLP). While topical steroids are common, no trials compared them to placebo. Aloe vera and cyclosporine showed weak evidence for pain relief in OLP.

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Last Updated: May 31, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
06:06

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

Published on: May 9, 2022

Area of Science:

  • Immunology
  • Dermatology
  • Autoimmune Diseases

Background:

  • Oral lichen planus (OLP) is a prevalent chronic autoimmune condition.
  • It stems from cell-mediated immunological dysfunction.
  • Symptomatic OLP causes pain, with rare complete healing.

Purpose of the Study:

  • To evaluate the efficacy and safety of various therapies for symptomatic OLP.
  • To identify treatments that effectively reduce pain associated with OLP.

Main Methods:

  • Systematic review of randomized controlled clinical trials (RCTs).
  • Searched Cochrane, CENTRAL, MEDLINE, and EMBASE databases without language or date restrictions.
  • Included RCTs comparing treatments to placebo, other interventions, or no intervention for symptomatic OLP.

Main Results:

  • 28 trials were included; pain was the primary outcome.
  • No RCTs compared topical steroids to placebo for OLP.
  • Pimecrolimus showed no benefit over placebo. Aloe vera and cyclosporine had weak evidence for pain reduction.
  • No significant difference in pain reduction was found between steroids and calcineurin inhibitors.

Conclusions:

  • No RCTs compared topical steroids to placebo for symptomatic OLP.
  • Evidence does not support one steroid being more effective than another.
  • Weak evidence suggests aloe vera may alleviate OLP pain and signs. Cyclosporine also shows weak evidence for pain and sign reduction.
  • Insufficient evidence exists to endorse any specific OLP treatment as superior.