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Related Concept Videos

Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Adrenergic Agonists: Therapeutic Uses01:30

Adrenergic Agonists: Therapeutic Uses

Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by anesthetizing...
Adrenergic Agonists: Therapeutic Classification01:18

Adrenergic Agonists: Therapeutic Classification

Adrenergic agonists can be classified based on their therapeutic uses and mechanisms of action. They serve various purposes in clinical applications.
Vasopressor or pressor agents: They increase blood pressure and function as cardiac stimulants. Examples include endogenous catecholamines (norepinephrine and dopamine) and synthetic agents (phenylephrine).
Bronchodilators: β2-agonists can relax bronchial muscles and widen airways. They are commonly used for treating obstructive pulmonary...

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Related Experiment Video

Updated: May 31, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Beta2-agonists for acute bronchitis.

Lorne A Becker1, Jeffrey Hom, Miguel Villasis-Keever

  • 1Department of Family Medicine, SUNY Upstate Medical University, 475 Irving Ave, Suite 200, Syracuse, NY, USA, 13210.

The Cochrane Database of Systematic Reviews
|July 8, 2011
PubMed
Summary
This summary is machine-generated.

Beta2-agonists offer no proven benefit for acute cough in children or adults without airflow obstruction. While potentially helpful for those with airflow issues, benefits are uncertain and side effects like nervousness are common.

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Methodology for Sputum Induction and Laboratory Processing
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Methodology for Sputum Induction and Laboratory Processing

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
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Methodology for Sputum Induction and Laboratory Processing
13:28

Methodology for Sputum Induction and Laboratory Processing

Published on: December 17, 2017

Area of Science:

  • Respiratory Medicine
  • Clinical Pharmacology

Background:

  • Acute bronchitis cough lacks effective treatments.
  • Beta2-agonists are sometimes prescribed for acute cough, assuming reversible airflow restriction.

Purpose of the Study:

  • To evaluate the efficacy of beta2-agonists for acute bronchitis symptoms in patients without underlying pulmonary disease.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs) comparing beta2-agonists to placebo or no treatment.
  • Searched CENTRAL, MEDLINE, and EMBASE databases.
  • Independent data extraction and risk of bias assessment.

Main Results:

  • No benefits found for oral beta2-agonists in children (n=109) without airway obstruction.
  • Adults (n=418) showed no significant improvement in cough scores or resolution with oral or inhaled beta2-agonists.
  • Increased risk of adverse effects like tremor and nervousness reported in adults.

Conclusions:

  • Beta2-agonists are not recommended for acute cough in children without airflow obstruction.
  • Limited evidence supports routine beta2-agonist use in adults with acute cough.
  • Potential benefits in patients with airflow obstruction require further investigation, balancing against adverse effects.