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Related Concept Videos

Neurotransmitters01:31

Neurotransmitters

Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
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Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Related Experiment Video

Updated: May 31, 2026

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding
09:12

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Published on: November 14, 2018

[Oxytocin and male sexual function].

Ruo-Bing Teng1, Xin-Hua Zhang

  • 1Institute of Urology and Nephrology, Guangxi Medical University, Nanning, Guangxi 530021, China.

Zhonghua Nan Ke Xue = National Journal of Andrology
|July 9, 2011
PubMed
Summary

Oxytocin (OT) influences male sexual activity, acting centrally to promote erection and peripherally to inhibit it. Targeting OT in the central nervous system may treat erectile dysfunction, while injections could help priapism.

Area of Science:

  • Neuroendocrinology
  • Reproductive Physiology

Context:

  • Oxytocin (OT) traditionally recognized for female reproductive roles.
  • Emerging evidence highlights OT's complex involvement in the central and peripheral nervous systems.
  • OT significantly impacts male reproductive physiology and sexual behaviors.

Purpose:

  • To review the multifaceted roles of oxytocin in male sexual activities.
  • To explore the dual (central and peripheral) effects of OT on penile erection.
  • To discuss the therapeutic potential of targeting OT pathways for male sexual dysfunction.

Summary:

  • Oxytocin exhibits a biphasic effect on penile erection: proerectile centrally and inhibitory peripherally.
  • OT modulates ejaculation, detumescence, and the post-orgasm refractory period.

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Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding
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Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Published on: November 14, 2018

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Measuring Skeletal Muscle Thermogenesis in Mice and Rats

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  • Central oxytocin and its receptor are identified as potential therapeutic targets for erectile dysfunction.
  • Intracavernous OT injection shows promise for treating priapism.

    • Impact:

    • Provides a comprehensive overview of oxytocin's function in male sexual physiology.
    • Identifies novel therapeutic strategies for erectile dysfunction and priapism.
    • Underscores the importance of oxytocin signaling in male reproductive health.