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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Related Experiment Video

Updated: May 31, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

[Hepatitis E as zoonosis].

Anna Baumann-Popczyk1

  • 1Zakład Epidemiologii Narodowego Instytutu Zdrowia Publicznego-Państwowego Zakładu Higieny w Warszawie. abaumann@pzh.gov.pl

Przeglad Epidemiologiczny
|July 9, 2011
PubMed
Summary

Hepatitis E virus (HEV) is a zoonotic disease transmitted from animals like pigs, boars, and deer to humans. Close contact with infected animals and consumption of undercooked meat pose significant risks for HEV infection.

Area of Science:

  • Virology
  • Zoonotic Diseases
  • Public Health

Context:

  • Hepatitis E virus (HEV) is a significant cause of acute hepatitis globally.
  • HEV is recognized as a zoonotic pathogen, with domestic pigs, wild boars, and deer identified as primary reservoirs.
  • HEV transmission occurs primarily through the oral-fecal route via contaminated food and water.

Purpose:

  • To consolidate evidence supporting the zoonotic nature of HEV.
  • To highlight the role of animal reservoirs in HEV transmission to humans.
  • To identify high-risk occupational groups and consumption patterns associated with HEV infection.

Summary:

  • HEV, a non-enveloped RNA virus, causes hepatitis E and is transmissible through contaminated food and water.
  • Genetic analysis of HEV strains from pigs and humans shows high similarity, confirming zoonotic transmission.

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Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

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Related Experiment Videos

Last Updated: May 31, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
09:02

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

  • Studies indicate increased HEV infection risk in veterinarians and swine breeders, and after consuming undercooked wild game.

    • Impact:

    • Provides a comprehensive understanding of HEV as a zoonosis.
    • Informs public health strategies for preventing HEV transmission from animal reservoirs.
    • Highlights the importance of food safety and occupational health measures to mitigate HEV risks.