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Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
Published on: March 23, 2013
Gastric pacing for diabetic gastroparesis--does it work?
M J Hannon1, S Dinneen, O Yousif
1Department of Endocrinology and Metabolism, Cork University Hospital, Wilton, Cork. markjhannon2002@yahoo.co.uk
Gastric electrical stimulation (GES) did not improve inpatient stays or glycaemic control in Irish patients with difficult diabetic gastroparesis. This study suggests GES may be ineffective for this patient group.
Area of Science:
- Gastroenterology
- Medical Devices
- Diabetes Management
Background:
- Diabetic gastroparesis resistant to medical therapy presents significant management challenges.
- Gastric electrical stimulation (GES) is an emerging therapeutic option with promising international trial results.
- Limited data exists on GES effectiveness in the Irish healthcare setting.
Purpose of the Study:
- To evaluate the impact of GES on inpatient stay duration and cost.
- To assess the effect of GES on glycaemic control (HbA1c) in patients with diabetic gastroparesis.
- To determine the overall efficacy of GES in a small cohort of Irish patients.
Main Methods:
- Retrospective case note review of four patients who underwent GES.
- Calculation of inpatient days for symptomatic gastroparesis pre- and post-GES.
- Analysis of total inpatient admission costs and average HbA1c levels before and after GES.
Main Results:
- Mean inpatient stay was 81.75 days pre-GES and 62.25 days post-GES (p=0.89), showing no significant difference.
- No improvement in glycaemic control (HbA1c) was observed following GES.
- GES demonstrated ineffectiveness in reducing inpatient stay duration and improving glycaemic control in this cohort.
Conclusions:
- Gastric electrical stimulation (GES) was ineffective in improving length of inpatient stay for diabetic gastroparesis patients in this study.
- GES did not lead to better glycaemic control in the evaluated patient cohort.
- Further research is needed to clarify the role of GES in managing refractory diabetic gastroparesis.
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