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Updated: May 31, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

Is neonatal group B streptococcal infection preventable?

M Azam¹, N M Allen, D O'Donovan

¹Department of Paediatrics, Galway University Hospital, Newcastle Road, Galway.

Irish Medical Journal

|July 9, 2011

Summary

Early onset group B streptococcal (EOGBS) infection remains a concern. This study found a low incidence of EOGBS at Galway University Hospital, with limited opportunities to improve intrapartum antibiotic (IAP) use for prevention.

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A Murine Model of Group B Streptococcus Vaginal Colonization

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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Area of Science:

Obstetrics and Gynecology
Neonatal Medicine
Infectious Diseases

Background:

Early onset group B streptococcal (EOGBS) infection is a major cause of newborn illness and death.
Galway University Hospital (GUH) employs a risk-based approach to prevent EOGBS.

Purpose of the Study:

To determine the incidence of EOGBS at GUH between 2004 and 2009.
To identify any missed opportunities for preventing neonatal EOGBS infections.

Main Methods:

Retrospective review of EOGBS cases and intrapartum antibiotic (IAP) administration.
Analysis of obstetric practices and potential for improved IAP usage.

Main Results:

The incidence of EOGBS was 0.45 per 1,000 live births.
One neonatal death and one case with neurological sequelae were recorded.
Only one mother received IAP; no clear opportunities for improving IAP use were identified.

Conclusions:

The incidence of EOGBS at GUH during the study period was low.
Current risk-based obstetric practices may be effective, but further evaluation of IAP strategies is warranted.