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Updated: May 31, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Basaloid squamous carcinoma with a spindle cell component and osseous metaplasia presenting as a polyp of the
Virginie Lavialle-Guillotreau1, Emmanuelle Uro-Coste, Annie Patelli
1Inserm U858, IFR 150, Équipe 15, laboratoire d'anatomie pathologique et d'histologie-cytologie, université Paul-Sabatier Toulouse III, CHU Rangueil, avenue Jean-Poulhès, 31059 Toulouse cedex 9, France. lavialle-guillotreau.v@chu-toulouse.fr
Abstract:
We report a case of basaloid squamous carcinoma with a spindle cell component of the hypopharynx, in a 61-years-old-man. An excisional biopsy of a pedonculated and polypoid tumour was performed by endoscopy. The histologic examination revealed a biphasic tumour with both a basaloid carcinomatous and a spindle cell component. Focally, osseous metaplasia was seen. The spindle cell component demonstrated immunoreactivity with the p63 epithelial marker. The patient was treated with chemotherapy followed by radiotherapy. The patient has been free of disease for one year. It's the ninth case reported in the literature of a biphasic carcinoma with both a basaloid squamous and a spindle cell component and the first case with osseous metaplasia.
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