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CytReD: A database collecting human cytokinome information
Bioinformation
|July 9, 2011
Summary
The Cytokine Receptor Database (CytReD) compiles data on cytokine receptors, their functions, and associated diseases. This resource aids researchers and clinicians in identifying key cytokines for disease diagnosis and prognosis.
Area of Science:
- Immunology
- Molecular Biology
- Bioinformatics
Background:
- Cytokine and related receptor systems are crucial in chronic inflammatory processes underlying diseases like cancer.
- Understanding these interactions is vital for disease management.
Purpose of the Study:
- To develop a comprehensive Cytokine Receptor Database (CytReD).
- To centralize information on cytokine receptors, including biological activity, gene data, protein structures, and implicated diseases.
Main Methods:
- Database development and curation.
- Integration of diverse data types including biological activity, genetic, structural, and clinical information.
- Making the database freely accessible online.
Main Results:
- CytReD provides a centralized repository of information on cytokine receptors.
- The database links cytokine receptors and their ligands to specific diseases.
- It includes data on biological activity, gene information, and protein structures.
Conclusions:
- CytReD serves as a valuable resource for researchers and clinicians.
- Facilitates the identification of critical cytokines for disease diagnosis and prognosis.
- Supports advancements in understanding and managing inflammatory diseases and cancers.
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