A case of reactive eccrine syringofibroadenoma

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Eccrine syringofibroadenoma is a rare adnexal neoplasm originating from eccrine ducts.
• It presents with diverse clinical and histopathological features, often mimicking other skin lesions.
• Understanding its etiology, particularly reactive forms, is crucial for accurate diagnosis.

Observation:

• A 37-year-old woman developed a lesion on her foot.
• The lesion appeared after self-inflicted tissue paring, leading to infection and ulceration.
• The clinical presentation included papules and nodules on the foot.

Findings:

• Histopathological examination confirmed eccrine syringofibroadenoma.
• The tumor exhibited anastomosing cords of cuboidal cells within a fibrovascular stroma.
• The development was deemed reactive, associated with prior trauma and infection.

Implications:

• This case expands the understanding of eccrine syringofibroadenoma's potential to arise reactively.
• It underscores the importance of considering iatrogenic or traumatic factors in adnexal tumor development.
• Further research into reactive adnexal tumors may reveal new diagnostic and therapeutic strategies.