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Related Experiment Video

Updated: May 31, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

Systemic contact dermatitis from propolis ingestion.

Eujin Cho¹, Jeong Deuk Lee, Sang Hyun Cho

¹Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Annals of Dermatology

|July 9, 2011

Summary

This summary is machine-generated.

Propolis, or bee glue, is used for its anti-inflammatory benefits. This report details the first known case of systemic contact dermatitis caused by ingesting propolis.

Keywords:

Allergic contact dermatitis Bee glue Propolis Systemic contact dermatitis

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Published on: September 26, 2022

Area of Science:

Immunology
Dermatology
Natural Products Chemistry

Background:

Propolis, a resinous hive product, is utilized by bees for construction and hygiene.
It possesses recognized anti-inflammatory properties, leading to its use in traditional and modern remedies.
Allergic contact dermatitis is a known adverse reaction to topical propolis exposure.

Observation:

A 36-year-old woman presented with generalized skin manifestations.
These symptoms were linked to the ingestion of propolis.
This represents a novel presentation of propolis-induced hypersensitivity.

Findings:

The patient developed systemic contact dermatitis following oral propolis consumption.
This case is the first documented instance of generalized cutaneous reactions from propolis ingestion.
Propolis allergy can manifest beyond localized contact dermatitis.

Implications:

Highlights the potential for systemic allergic reactions to propolis, even when ingested.
Suggests a need for increased awareness among healthcare providers regarding propolis hypersensitivity.
Underscores the importance of considering dietary factors in the differential diagnosis of widespread dermatitis.