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Updated: May 31, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Systemic contact dermatitis from propolis ingestion
Eujin Cho1, Jeong Deuk Lee, Sang Hyun Cho
1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract:
Propolis, also known as bee glue, is a substance collected by worker bees and it is used as a material for constructing and maintaining their beehives. It has been used topically and orally by humans for its anti-inflammatory properties. However, the growing use of propolis has been paralleled by reports of allergic contact dermatitis as a reaction to the substance. Contact dermatitis with generalized cutaneous manifestations elicited by propolis ingestion has not been previously reported. Here we report on the first case of systemic contact dermatitis from propolis ingestion in a 36-year-old woman.
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