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Extensive Spinal Cord Injury following Staphylococcus aureus Septicemia and Meningitis
Nicolas De Schryver1, Guy Cosnard, Vincent van Pesch
1Intensive Care, Université catholique de Louvain, Brussels, Belgium.
Abstract:
Bacterial meningitis is rarely complicated by spinal cord involvement in adults. We report a case of Staphylococcus aureus septicemia complicated by meningitis and extensive spinal cord injury, leading to ascending brain stem necrosis and death. This complication was investigated by magnetic resonance imaging which demonstrated intramedullary hyperintensity on T2-weighted images and by multimodality evoked potentials. Postmortem microscopic examination confirmed that the extensive spinal cord injury was of ischemic origin, caused by diffuse leptomeningitis and endarteritis.
Insights
Staphylococcus aureus meningitis rarely causes spinal cord injury in adults. This case highlights ischemic spinal cord injury from meningitis, leading to fatal brain stem necrosis.
Area of Science:
- Neurology
- Infectious Diseases
- Pathology
Background:
- Bacterial meningitis is an infection of the membranes surrounding the brain and spinal cord.
- Spinal cord involvement in adult bacterial meningitis is uncommon.
- Staphylococcus aureus septicemia can lead to severe complications.
Observation:
- A case of Staphylococcus aureus septicemia complicated by meningitis and extensive spinal cord injury is presented.
- The patient experienced ascending brain stem necrosis and death.
- Magnetic resonance imaging revealed intramedullary hyperintensity on T2-weighted images.
- Multimodality evoked potentials were used for investigation.
Findings:
- Postmortem examination confirmed extensive spinal cord injury of ischemic origin.
- The injury was attributed to diffuse leptomeningitis and endarteritis.
- This indicates a rare but severe neurological complication of bacterial meningitis.
Implications:
- This case underscores the potential for severe spinal cord complications in bacterial meningitis.
- Early recognition and management of meningitis complications are crucial.
- Further research into the mechanisms of spinal cord injury in meningitis may be warranted.
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