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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)
Published on: December 19, 2019
Cutaneous tuberculosis and squamous-cell carcinoma
Milanka S Ljubenovic1, Dragisa B Ljubenovic, Ivana I Binic
1Clinic of Dermatovenereology, Nis, Serbia and Stomatology Clinic, Department of Maxillofacial Surgery, Nis, Serbia milanka_ljubenovic@yahoo.com
Anais Brasileiros De Dermatologia
|July 9, 2011
Summary
Cutaneous tuberculosis, though declining, still requires accurate diagnosis and management. Untreated lupus vulgaris can potentially lead to squamous cell carcinoma, as seen in this case report.
Area of Science:
- Dermatology
- Oncology
- Infectious Diseases
Background:
- Cutaneous tuberculosis incidence declined in the 20th century due to improved living standards and therapies.
- Lupus vulgaris remains the most common form of cutaneous tuberculosis.
- Accurate diagnosis and management are crucial for patient health and public safety.
Observation:
- A 74-year-old male farmer presented with facial lupus vulgaris.
- During anti-tuberculosis treatment, a forehead tumor developed.
- The tumor was histologically confirmed as squamous cell carcinoma.
Findings:
- Long-standing or untreated cutaneous tuberculosis poses a risk for developing cancers.
- This case highlights a potential link between lupus vulgaris and squamous cell carcinoma.
Implications:
- Emphasizes the importance of vigilant monitoring and complete treatment of cutaneous tuberculosis.
- Suggests a need for increased awareness among clinicians regarding the oncogenic potential of chronic skin infections.
- Underscores the significance of early cancer detection in patients with a history of tuberculosis of the skin.
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