Related Experiment Video
Updated: May 31, 2026

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome
Published on: March 23, 2022
Do you know this syndrome?
Isabela Guimarães Ribeiro Baeta1, Ana Carolina Figueiredo Pereira, Antônio Carlos Martins Guedes
1Dermatology Outpatient Department, Teaching Hospital of the Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. lucianabpereira@terra.com.br
Abstract:
Keratosis linearis with ichthyosis congenita and sclerosing keratoderma (KLICK) syndrome is a rare autosomal recessive skin disorder characterized by the association of diffuse, transgressive palmoplantar keratoderma with sclerodactyly, linear hyperkeratotic plaques generally located in flexures, and congenital ichthyosis. The patient is physically and mentally healthy and has no history of any problems related to teeth, nails, hair or mucous membranes. Treatment is based on the use of topical keratolytics and oral retinoids.
Related Concept Videos
Cushing Syndrome II: Pathophysiology
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Cushing Syndrome I: Introduction
Social Anxiety Disorder
Panic Disorder
Obsessive-Compulsive Disorder
