Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...
Social Anxiety Disorder01:28

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Detection of viral antigen and inflammatory mediators in fatal pediatric dengue: a study on lung immunopathogenesis.

Frontiers in immunology·2025
Same author

Evaluation of underreporting occupational accidents among workers who handle laboratory animals.

Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT·2025
Same author

Molecular monitoring by CDKN2A/p16INK4A and RB1 gene methylation in breast cancer.

Revista da Associacao Medica Brasileira (1992)·2024
Same author

Liver immunopathogenesis in fatal cases of dengue in children: detection of viral antigen, cytokine profile and inflammatory mediators.

Frontiers in immunology·2023
Same author

Immunopathology of Renal Tissue in Fatal Cases of Dengue in Children.

Pathogens (Basel, Switzerland)·2022
Same author

Validation and reproducibility of the International Study of Asthma and Allergies in Childhood (ISAAC) Written Atopic Eczema Questionnaire for telephone survey in children aged 6-7 years.

Anais brasileiros de dermatologia·2022
Same journal

Correlation between invasion front and survival of patients with cutaneous melanomas.

Anais brasileiros de dermatologia·2026
Same journal

Nanocarriers for topical minoxidil in androgenetic alopecia: systematic review of preclinical and clinical evidence.

Anais brasileiros de dermatologia·2026
Same journal

Pediatric psoriasis: from immunogenetics to targeted therapies.

Anais brasileiros de dermatologia·2026
Same journal

Perifollicular fibrosis and inflammation in androgenetic alopecia and seborrheic dermatitis: diagnostic challenges in differentiation from fibrosing alopecia in a pattern distribution.

Anais brasileiros de dermatologia·2026
Same journal

Exuberant cutaneous lymphoepithelioma-like carcinoma: clinicopathological correlation in an aggressive case<sup>⋆</sup>.

Anais brasileiros de dermatologia·2026
Same journal

Tumor-like periungual cutaneous sporotrichosis in an endemic area.

Anais brasileiros de dermatologia·2026
See all related articles

Related Experiment Video

Updated: May 31, 2026

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome
06:48

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Published on: March 23, 2022

Do you know this syndrome?

Isabella Brasil Succi1, Fernando Colonna Rosman, Elisa Fontenelle de Oliveira

  • 1Hospital Municipal Jesus (HMJ), Rio de Janeiro, Brazil. ibsucci@unisys.com.br

Anais Brasileiros De Dermatologia
|July 9, 2011
PubMed
Summary
This summary is machine-generated.

Bloch-Sulzberger syndrome, also known as incontinentia pigmenti, is a rare genetic skin disorder primarily affecting females. This condition presents with distinct skin lesion phases and can involve other systemic abnormalities.

More Related Videos

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Related Experiment Videos

Last Updated: May 31, 2026

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome
06:48

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Published on: March 23, 2022

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Area of Science:

  • Dermatology
  • Genetics
  • Pediatrics

Background:

  • Bloch-Sulzberger syndrome (incontinentia pigmenti) is a rare genodermatosis.
  • This condition predominantly affects females due to its typically lethal impact on male fetuses.

Observation:

  • The syndrome is primarily characterized by specific skin lesions.
  • Additional abnormalities can manifest in dental, ophthalmological, and neurological systems.

Findings:

  • Skin lesions progress through four distinct phases: vesicular, verrucous, hyperpigmented, and atrophic/hypopigmented.
  • The sequence of these phases is irregular, with common overlapping of stages.

Implications:

  • Understanding the phased progression aids in diagnosis and management of Bloch-Sulzberger syndrome.
  • Early identification of associated systemic abnormalities is crucial for comprehensive patient care.