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Updated: May 31, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Atrium-atrioventricular node block: an unusual complication during catheter ablation of persistent atrial
Cheng-Long Miao1, Cai-Hua Sang, Jian-Zeng Dong
1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
Insights
Extensive catheter ablation for persistent atrial fibrillation can cause complications. This case highlights the risk of atrioventricular block after complex ablation, especially involving the interatrial septum.
Area of Science:
- Electrophysiology
- Cardiac Ablation
- Atrial Fibrillation Management
Background:
- Persistent atrial fibrillation necessitates complex ablation strategies.
- Extensive ablation, including pulmonary vein, linear, and fractionated atrial electrogram ablation, is sometimes required.
- Complications can arise from extensive cardiac ablation procedures.
Observation:
- A case of complete atrioventricular block occurred after multiple catheter ablation procedures for persistent atrial fibrillation.
- The patient underwent extensive ablation, including circumferential pulmonary vein ablation, left atrial roof and mitral isthmus linear ablation, atrial septum ablation, cavotricuspid isthmus ablation, and complex fractionated atrial electrogram ablation.
- A conduction obstacle was identified, preventing sinus impulse transmission from the atria to the atrioventricular node.
Findings:
- Intensive ablation, particularly at the interatrial septum, can lead to unintended complications such as atrioventricular block.
- The observed conduction block suggests significant damage or alteration of atrial pathways.
- Careful consideration of ablation strategy at critical atrial sites is crucial.
Implications:
- This case underscores the importance of cautious and strategic ablation, especially in the interatrial septum, during atrial fibrillation treatment.
- Understanding potential complications like atrioventricular block is vital for electrophysiologists performing complex ablations.
- Refined ablation techniques may be needed to minimize risks while effectively treating persistent atrial fibrillation.
Abstract:
Ablation of persistent atrial fibrillation is still a challenge for the ablationist. Extensive ablation is required under some conditions and could lead to some unintended complications. Here we report a case of atrium-atrioventricular node block complicating multiple catheter ablation procedures for persistent atrial fibrillation. After extensive ablation, including circumferential pulmonary vein ablation, linear ablation at the left atrial roof, mitral isthmus, atrial septum, cavotricuspid isthmus, and complex fractionated atrial electrogram ablation, conduction obstacle was found, and sinus impulse could not travel from the right atrium, atrial septum and left atrium to atrioventricular node. The case indicated that intensive ablation at some key sites, especially the interatrial septum, should be careful during ablation of atrial fibrillation.
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