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Life expectancy among persons with schizophrenia or bipolar affective disorder
1National Centre for Register-Based Research, Aarhus University, Taasingegade 1, 8000 Aarhus C, Denmark. tml@ncrr.dk
Context:
Mortality rates among individuals with schizophrenia or bipolar disorder are elevated compared to the general population.
Objective:
The objective was to estimate life-expectancy (average age at death) among these persons and make a comparison to people in the general population.
Methods:
Life-expectancy was calculated by means of survival analysis techniques using the entire Danish population as a cohort.
Results:
Life-expectancy was 18.7 years shorter for schizophrenic men compared to men in the general population. Corresponding numbers for schizophrenic women was 16.3 years, for bipolar men 13.6 years, and for bipolar women 12.1 years.
Conclusions:
Life-expectancy was much shorter in persons with schizophrenia or bipolar disorder. Excess mortality from physical diseases and medical conditions exerts a far greater influence on the curtailed life-expectancy, when compared against the impact of death by external causes.
Related Concept Videos
Schizophrenia
Bipolar Disorder
Psychological and Sociocultural Causes of Schizophrenia
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Biological Causes of Schizophrenia
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.