Surgical treatment for nontuberculous mycobacterial (NTM) cervicofacial lymphadenitis in children

Jerome A H Lindeboom1

  • 1Department of Oral and Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, Academic Center for Dentistry Amsterdam, Amsterdam, The Netherlands. j.a.lindeboom@amc.uva.nl

Insights

Surgical excision offers faster healing for nontuberculous mycobacterial (NTM) cervicofacial lymphadenitis in children compared to curettage. While excision is quicker, curettage may be safer if facial nerve branches are adhered to.

Area of Science:

  • Pediatric infectious diseases
  • Surgical treatments for lymphadenitis
  • Mycobacterial infections

Background:

  • Nontuberculous mycobacterial (NTM) cervicofacial lymphadenitis is a common infection in children.
  • Treatment options include surgical intervention, with varying outcomes.
  • Comparing surgical excision and curettage is crucial for optimizing patient care.

Purpose of the Study:

  • To compare the efficacy of surgical excision versus surgical curettage in treating pediatric cervicofacial NTM lymphadenitis.
  • To evaluate wound healing times and postoperative complications associated with each surgical method.

Main Methods:

  • A randomized study involving 50 children diagnosed with cervicofacial NTM infection.
  • Participants were assigned to either surgical excision (25 children) or surgical curettage (25 children).
  • PCR or culture confirmation of NTM infection was required for inclusion.

Main Results:

  • Surgical excision demonstrated significantly faster wound healing (3.6 weeks) compared to curettage (11.4 weeks).
  • Transient marginal mandibular nerve weakness occurred in 16% of the excision group, with full recovery within 12 weeks.
  • No facial nerve issues or postoperative infections were reported in the curettage group.

Conclusions:

  • Surgical excision provides a more rapid resolution of NTM cervicofacial lymphadenitis in children.
  • Surgical curettage, though associated with delayed healing, presents a viable alternative when nerve adherence complicates excision.
  • Careful consideration of potential nerve involvement is essential when selecting the surgical approach.
Abstract