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Metabolism of quercetin by Cunninghamella elegans ATCC 9245
Jiachen Zi1, Jonathan Valiente, Jia Zeng
1Department of Biological Engineering, Utah State University, Logan, UT 84322-4105, USA.
Abstract:
Incubation of quercetin with Cunninghamella elegans ATCC 9245 yielded three metabolites, including quercetin 3-O-β-D-glucopyranoside, kaempferol 3-O-β-D-glucopyranoside and isorhamnetin 3-O-β-D-glucopyranoside. Glucosylation, O-methylation and dehydroxylation were involved in the process, among which dehydroxylation has never been found in Cunninghamella. Quercetin was completely metabolized in 72 h.
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