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Related Experiment Video

Updated: May 31, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Repeat radiosurgery for intracranial arteriovenous malformations.

John M Stahl1, Yueh-Yun Chi, William A Friedman

  • 1Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA.

Neurosurgery
|July 12, 2011
PubMed
Summary

Repeat radiosurgery effectively treats failed intracranial arteriovenous malformations (AVMs). This salvage treatment achieved a 65.3% obliteration rate with manageable complications, offering a safe option for persistent AVMs.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Vascular Neurology

Background:

  • Intracranial arteriovenous malformations (AVMs) treated with stereotactic radiosurgery have a high success rate.
  • However, some patients require management following treatment failure.

Purpose of the Study:

  • To update on the efficacy of repeat linear accelerator radiosurgery for failed AVM radiosurgery.
  • This study focuses on outcomes at the University of Florida.

Main Methods:

  • A retrospective review of 103 patients who received repeat radiosurgery for residual AVMs between 1991 and 2007.
  • Data collected included AVM volume, dose, patient demographics, and follow-up imaging (MRI, CT, angiography).
  • Median follow-up after retreatment was 31 months.

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Last Updated: May 31, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
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Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Facilitating Repeat Intracarotid Injections in Mouse Models by a Novel Injection Site Repair Technique
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Main Results:

  • Median AVM nidus volume decreased by 69% between treatments, allowing for increased radiation dosage.
  • The final obliteration rate after repeat radiosurgery was 65.3%.
  • Complications included radiation-induced issues (4.9%) and posttreatment hemorrhage (5.8%).

Conclusions:

  • Repeat radiosurgery is a safe and effective salvage treatment for intracranial arteriovenous malformations.
  • This approach offers a viable option for patients with residual AVMs after initial radiosurgical failure.