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The genetics of affective disorder - a pedigree study
T S Rao1, V S Rao, S Shivamoorthy
1T.S. Sathyanarayana Rao, MD, DPM, Associate Professor & Head, Department of Psychiatry, J.S.S. Medical College & Hospital, Ramanuja Road, Mysore - 570 004.
Abstract:
A study on the genetics of effective disorder was carried out using pedigree methodology. Ike index case presented with features of bulimia which was diagnosed to be Bipolar affective disorder. The pedigree was analyzed for 4 generations and included evaluation of 76 individuals, of whom the oldest was 103 years of age. The evaluation was done clinically to demonstrate various concepts concerning affective syndromes, the presence and extent of gene borne influences and mode of inheritance. Data was compared with other genetic research studies and suggestions for further research arc made.
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