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Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
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Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...
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Positive Symptoms Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
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Microbial Interactions: Parasitism01:22

Microbial Interactions: Parasitism

Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...
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Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
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Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...

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Investigating the Phagocytosis of Leishmania using Confocal Microscopy
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Delusional parasitosis in leprosy.

S Shome1, R Chadda, M Ramam

  • 1Sabita Shome, MD, Senior Resident, Department of Psychiatry, University of College of Medical Sciences & GTB Hospital, Shahdara, Delhi - 100 095.

Indian Journal of Psychiatry
|July 12, 2011
PubMed
Summary

Leprosy can trigger delusional parasitosis in patients. Neuritic leprosy manifestations may precipitate the onset of these delusions, highlighting a neurological link.

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Area of Science:

  • Neurology
  • Psychiatry
  • Dermatology

Background:

  • Leprosy is a chronic infectious disease primarily affecting peripheral nerves, skin, and mucous membranes.
  • Delusional parasitosis is a psychiatric disorder characterized by the fixed, false belief of being infested with parasites.

Purpose of the Study:

  • To describe a case of leprosy co-occurring with delusional parasitosis.
  • To explore the potential role of neuritic leprosy manifestations in triggering delusional symptoms.

Main Methods:

  • Case report detailing clinical presentation, diagnostic process, and treatment of a patient with both conditions.
  • Review of relevant literature on leprosy, neuritic manifestations, and delusional parasitosis.

Main Results:

  • The patient presented with symptoms of both leprosy and delusional parasitosis.
  • Neuritic manifestations of leprosy were observed, suggesting a potential trigger for the delusional symptoms.

Conclusions:

  • Leprosy, particularly its neuritic forms, may act as a precipitating factor for delusional parasitosis.
  • This case underscores the complex interplay between neurological and psychiatric symptoms in infectious diseases.