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Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

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Related Experiment Video

Updated: May 31, 2026

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
09:09

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Published on: March 14, 2019

Osteitic bone in recalcitrant chronic rhinosinusitis.

W J M Videler1, C Georgalas, D J Menger

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Academic Medical Centre (AMC), Amsterdam, the Netherlands. W.J.Videler@amc.uva.nl

Rhinology
|July 12, 2011
PubMed
Summary

Osteitis, or bone inflammation, is linked to Chronic Rhinosinusitis (CRS). While associated with CRS, its exact role in the disease process requires further investigation.

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Area of Science:

  • Otolaryngology
  • Pathology

Background:

  • Chronic Rhinosinusitis (CRS) is increasingly linked to the underlying paranasal sinus bone.
  • CT scans often show increased bone density and thickened sinus walls in CRS patients, suggesting osteitis.
  • This osteitic bone may contribute to persistent mucosal inflammation.

Purpose of the Study:

  • To review the current understanding of osteitis in Chronic Rhinosinusitis.
  • To discuss diagnostic options, treatment implications, and future research directions.

Main Methods:

  • A comprehensive literature search was conducted using PubMed.
  • Keywords included: chronic rhinosinusitis, sinusitis, bone, osteitis, osteomyelitis, histology, and treatment.
  • References from retrieved articles were also examined.

Main Results:

  • The review discusses background information and available data on osteitis in CRS.
  • Potential diagnostic methods and treatment implications are explored.
  • Suggestions for future research are provided.

Conclusions:

  • Osteitis is associated with Chronic Rhinosinusitis.
  • The precise role of osteitis in the pathogenesis of CRS is not yet well-defined.
  • Further research is necessary to elucidate the connection between osteitis and CRS.