Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Development of the Oral Microbiota

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

CD28 ligation prevents bacterial toxin-induced septic shock in mice by inducing IL-10 expression.

Journal of immunology (Baltimore, Md. : 1950)·1997

Same author

MR imaging of tubercular spinal arachnoiditis.

AJR. American journal of roentgenology·1997

Same author

Interactions between transvenous nonthoracotomy cardioverter defibrillator systems and permanent transvenous endocardial pacemakers.

Pacing and clinical electrophysiology : PACE·1997

Same author

Role of the carboxyl-terminal region of Porphyromonas gingivalis fimbrillin in binding to salivary proteins.

Infection and immunity·1997

Same author

Phenethyl isothiocyanate modulates clastogenicity of mitomycin C and cyclophosphamide in vivo.

Mutation research·1996

Same author

Expression of functional Porphyromonas gingivalis fimbrillin polypeptide domains on the surface of Streptococcus gordonii.

Applied and environmental microbiology·1996

Search research articles

Related Experiment Video

Updated: May 31, 2026

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

Published on: January 13, 2023

Perinatal mortality audit.

S Shrestha¹, A Sharma, S Upadhyay

¹Department of Pediatrics, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal. sabinajoshi1234@hotmail.com

Nepal Medical College Journal : NMCJ

|July 13, 2011

Summary

This summary is machine-generated.

Perinatal mortality, a key indicator of healthcare quality, remains high due to factors like low birth weight and preterm birth. Improving neonatal care and antenatal checkups is crucial for reducing these preventable deaths.

More Related Videos

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Related Experiment Videos

Last Updated: May 31, 2026

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

Published on: January 13, 2023

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Transcutaneous Microcirculatory Imaging in Preterm Neonates

Published on: December 31, 2015

Area of Science:

Obstetrics and Gynecology
Neonatalogy
Public Health

Background:

Perinatal mortality rate serves as a critical indicator of maternal and neonatal healthcare quality.
Regular perinatal audits are essential for identifying factors contributing to perinatal deaths and implementing targeted interventions.
Previous studies indicate varying rates of perinatal mortality, necessitating ongoing research and quality improvement initiatives.

Purpose of the Study:

To analyze perinatal mortality indices in a tertiary care hospital in Nepal.
To identify common causes and risk factors associated with perinatal deaths.
To provide recommendations for reducing avoidable perinatal mortality.

Main Methods:

A retrospective study design was employed, analyzing data from 816 births over a one-year period (April 2007-March 2008).
Perinatal indices, including stillbirths and early neonatal deaths, were collected and analyzed.
Causes of death were categorized using Wigglesworth's classification, and risk factors such as birth weight and gestational age were examined.

Main Results:

The overall perinatal mortality rate was 26.9 per 1000 births.
Common causes included breech presentation with a stuck head and respiratory distress syndrome in preterm infants.
Low birth weight (<2500g) and preterm birth (<37 weeks gestation) were significant risk factors, accounting for 76.5% of perinatal deaths and 82% of early neonatal deaths.

Conclusions:

While the perinatal mortality rate is comparable to other studies, significant proportions of deaths are linked to low birth weight and preterm births.
There is a critical need to enhance neonatal care services and promote regular antenatal checkups to reduce preventable perinatal and neonatal mortality.
Targeted interventions focusing on high-risk pregnancies and improved neonatal support are essential for improving outcomes.